How to Spend More Time in Range with Omnipod® 5
Did you know, Omnipod 5 users with optimized settings spent over 80% Time in Range?1
Watch Scott Benner of the Juicebox Podcast to learn how optimized settings can support better results.
1 Retrospective RWE data on file. 2025. Results shown for users with optimized settings including sufficient CGM data (≥75% of days with≥220 readings), ≥90% time in Automated Mode, ≥5 bolus/day and an average Target Glucose of 110-115 mg/dL (6.1-6.4 mmol/L). Optimized settings: ISF x TDI ≤1500, I:C Ratio x TDI ≤350. RF-062025-00014.
How it works
Omnipod 5 automatically adjusts your insulin delivery, helping to keep your glucose levels in range.2-4
The system understands how much insulin to deliver automatically by looking at your total daily insulin (TDI) needs.
There are 3 settings you can use to increase insulin delivery responsiveness in Automated Mode:
Target Glucose
Insulin to Carb Ratio
Correction Factor
Always discuss with your healthcare professional before making adjustments to your insulin therapy. This page is intended for educational purposes only and does not constitute medical advice.
Optimizing Your Settings
Lower Target Glucose for more Time in Range5
Target Glucose is the key setting that impacts automated insulin delivery directly.
Target Glucose: In Automated Mode, insulin delivery will be adjusted automatically according to your Target Glucose value. Lowering your Target Glucose value tells the system to deliver more insulin.
Strengthening meal and correction bolus settings
Bolus settings impact automated insulin delivery indirectly. Getting more insulin for meal and correction boluses increases your TDI, which increases the system's insulin delivery responsiveness in Automated Mode.
Insulin to Carb Ratio: Number of grams of carbohydrates covered by one unit of insulin. Strengthening your I:C Ratio tells the system to give more insulin when you give a meal bolus.
Example: Changing I:C ratio from 1:10 to 1:9 gives more insulin for meal boluses*
Correction Factor: A value that indicates how much one unit of insulin will lower your blood glucose. Strengthening your Correction Factor tells the system to deliver more insulin for high glucose levels when you give a correction bolus.
Example: Changing Correction Factor from 1:50 to 1:40*
To make changes to these settings Select Menu → Bolus settings.
*These examples are for demonstration only. Your actual settings may vary.
Omnipod 5 Series on the Juicebox Podcast
Explore more Omnipod 5 optimization videos and Podcast episodes hosted by Scott Benner.
Looking for more Omnipod 5 resources?
Check out our most popular Omnipod 5 resources using the links below.
Omnipod 5 Quick Tips
Omnipod 5 FAQs
Omnipod 5 Video Tutorials
Live Chat Support
Many of your questions can be answered quickly through Live Chat (8am-10pm ET), which can be accessed on support pages or by logging into your PodderCentral. Click the small purple box on the bottom right corner of the screen to start a chat.
You can also reach Product Support 24/7 by calling 1-800-591-3455.
2 Brown S. et al. Diabetes Care (2021). Study in 240 people with T1D aged 6 - 70 years involving 2 weeks standard diabetes therapy followed by 3 months Omnipod 5 use in Automated Mode. Average time in Target Glucose range (from CGM) for standard therapy vs Omnipod 5 in adults/adolescents and children = 64.7% vs. 73.9%; 52.5% vs. 68.0%.
3 Sherr JL, et al. Diabetes Care (2022). Study in 80 people with T1D aged 2 - 5.9 yrs involving 2 weeks standard diabetes therapy followed by 3 months Omnipod 5 use in Automated Mode. Average time in Target Glucose range (from CGM) for standard therapy vs Omnipod 5 = 57.2% vs. 68.1%.
4 Pasquel FJ, et al. JAMA Network Open (2025). Prospective pivotal trial in 305 participants with T2D aged 18-75 yrs. Study included a 14-day standard therapy (ST) phase followed by a 13-week Omnipod 5 hybrid closed-loop phase. Mean time in range (70-180 mg/dL): ST vs. 13-week Omnipod 5: 45% vs. 66%, P<0.001.
5 Forlenza G, et al. Presented at: ATTD; March 19-22, 2025; Amsterdam, NL. Real-world data from 403 people with T1D aged 2+, and 58 people with T2D aged 18+ using the Omnipod 5 System who transitioned from the 150 mg/dL to 110 mg/dL Target Glucose. Each Target Glucose was used for a consecutive period of 14-90 days. Median time in Range (70-180 mg/dL) improved 11.8% (p<0.05). Median time in Range (70-180 mg/dL) improved 10.4% (p<0.05). Omnipod 5 results based on users with ≥75% of days with ≥220 readings available. Data on File. 05.15.25. RF-042025-00013
The Omnipod® 5 Automated Insulin Delivery System is indicated for use by individuals with type 1 diabetes mellitus in persons 2 years of age and older and type 2 diabetes mellitus in persons 18 years of age and older. The Omnipod 5 System is intended for single patient, home use and requires a prescription. The Omnipod 5 System is compatible with the following U-100 insulins: NovoLog®, Humalog®, Admelog®, and Kirsty®.
Refer to the Omnipod 5 Automated Insulin Delivery System User Guide and www.omnipod.com/safety for complete safety information including indications, contraindications, warnings, cautions, and instructions. Warning: DO NOT start to use the Omnipod 5 System or change settings without adequate training and guidance from a healthcare provider. Initiating and adjusting settings incorrectly can result in over-delivery or under-delivery of insulin, which could lead to hypoglycemia or hyperglycemia. WARNING: SmartAdjust technology should NOT be used by anyone under the age of 2 years old. SmartAdjust technology should also NOT be used in people who require less than 5 units of insulin per day as the safety of the technology has not been evaluated in this population.
Available products subject to current insurance coverage and product indication for use. Insulet can only support onboarding for those customers within the product indication.