Automated Insulin Delivery, Explained.

Automated Insulin Delivery (AID) is revolutionizing the way people manage their type 1 diabetes.

What is Automated Insulin Delivery?

AID systems, also known as Hybrid Closed Loop (HCL) systems, use an insulin pump and a compatible glucose sensor that ‘communicate’ to automatically deliver insulin based on real-time glucose information. 

AID uses smart software known as a control algorithm to frequently adjust basal insulin doses in small amounts, continuously calculating how much insulin to deliver as the user’s glucose levels fluctuate.

With this precise and personalized dosing, automated insulin delivery can improve glucose control and reduce A1c, in addition to reducing some of the burden of diabetes management1-3

How does Automated Insulin Delivery work?

An automated insulin delivery (AID) system is made up of three main parts:

  1. An insulin pump or Pod
  2. A compatible glucose sensor 
  3. Smart software, known as a control algorithm

Omnipod 5 Aid Infographic 1799x948 Omnipod 5 Aid Infographic 1799x948

AID allows for a complete circle of communication between the Pod or Pump, the glucose sensor and the control algorithm.

In simple terms, the sensor talks to the Pod or Pump, where the algorithm then responds by automatically increasing, decreasing or pausing insulin delivery depending on whether glucose levels are rising or falling.

Over time, the system learns more about your body’s total daily insulin needs to make predictions about your glucose levels. But Hybrid Closed Loop (HCL) AID systems are not fully automatic - you still need to bolus insulin for food. 

Click on below to find out more about insulin pumps and glucose sensors or read on to learn how they work together with the algorithm in an AID system!

 

Automated Insulin Delivery in practice

Generally, every 5 minutes:

  • The glucose sensor reports your glucose levels to the algorithm.
  • The algorithm calculates whether insulin delivery needs to be increased, decreased, remain the same or stopped completely.
  • The Pump or Pod actions the calculation.
  • The sensor picks up on any changes to your glucose level and reports that to the algorithm… and the circle continues. Which is the reason for the term ‘loop’.

How does this help people with type 1 diabetes?

AID systems are an exciting development in diabetes technology because the automated adjustments to insulin delivery can help to control blood glucose levels, reduce hypoglycaemia (low blood sugars) and increase time in range1-3.

 

An AID system can help lessen the burden of managing your diabetes, as well as helping to reduce highs and lows throughout the day and night1-3.

There are several automated insulin delivery systems now available, so speak to your diabetes team about your options.

Is the Omnipod right for me?

Frequently Asked Questions about Automated Insulin Delivery System

What is the Omnipod 5 Automated Insulin Delivery System?

Is an AID system the same as a Hybrid Closed-Loop system?

Jessica Sparks Lilley (pediatric endocrinologist)

Article by

Jessica Sparks Lilley (pediatric endocrinologist)

Last updated 11/19/2025

Jessica Sparks Lilley is a pediatric endocrinologist and the senior manager of field medical affairs at Insulet Corporation. She was drawn to her career field by beloved family members who were diagnosed in early childhood with T1DM. She trained at Vanderbilt Children’s Hospital and the Children’s Hospital of Philadelphia. Her passion for her home state drew her to practice in rural Mississippi for 13 years, first building an academic satellite clinic then a new multispecialty clinic with far-flung outreach, each from the ground up. She had a regular column in Medscape, “It’s a Small World,” on a variety of topics in pediatric endocrinology. Her research focused on diabetes numeracy and inherited lipid disorders. She has actively supported Breakthrough T1D and the Diabetes Foundation of Mississippi. She is passionate about expanding access of diabetes technology to people living with diabetes and joined Insulet in 2024 after seeing the transformative impact of automated insulin delivery in her patients and loved ones.

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References and Disclaimers

The information and other content provided in this article, or in any linked materials, are not intended and should not be construed as medical advice, nor is the information a substitute for professional medical expertise or treatment. If you or any other person has a medical question or concern, you should consult with your healthcare provider. Never disregard professional medical advice or delay in seeking it because of something that have read on this blog or in any linked materials. If you think you may have a medical emergency, call your doctor or emergency services immediately. The opinions and views expressed on this blog and website have no relation to those of any academic, hospital, health practice or other institution.


*A separate prescription is required for the glucose sensor.
† Bolus for meals and corrections are still needed.
§ Fingerpricks required for diabetes treatment decisions if symptoms or expectations do not match readings.
‡The Pod has a waterproof IP28 rating for up to 7.6 metres for 60 minutes. The Controller is not waterproof. Please refer to the sensor manufacturer’s user guide for individual guidance.
1 ADA Standards of Medical Care in Diabetes – 2021. Diabetes Care. 2021;44(S1):S1-S232.

2. Study in 240 people with T1D aged 6 - 70 years involving 2 weeks standard diabetes therapy followed by 3 months Omnipod 5 use in Automated Mode. Average overnight time (12AM-6AM) with high blood glucose in adults/adolescents and children for standard therapy vs Omnipod 5 = 32.1% vs. 20.7%; 42.2% vs. 20.7%. Average day time (6AM-12AM) with high blood glucose in adults/adolescents and children for standard therapy vs Omnipod 5 = 32.6% vs. 26.1%; 46.4% vs. 33.4%. Median overnight time (12AM-6AM) with low blood glucose in adults/adolescents and children for standard therapy vs Omnipod 5 = 2.07% vs. 0.82%; 0.78% vs. 0.78%. Median day time (6AM-12AM) with low blood glucose in adults/adolescents and children for standard therapy vs Omnipod 5 = 1.91% vs. 1.08%; 1.17% vs. 1.62%. Average A1c in adults/adolescents and children, standard therapy vs. Omnipod 5 = 7.16% vs 6.78%; 7.67% vs 6.99%. Brown S. et al. Diabetes Care (2021).

3. Study in 80 people with T1D aged 2 - 5.9 yrs involving 2 weeks standard diabetes therapy followed by 3 months Omnipod 5 use in Automated Mode. Average time with high blood glucose overnight from CGM in standard therapy vs Omnipod 5 = 38.4% vs. 16.9%. Average time with high blood during daytime from CGM in standard therapy vs Omnipod 5 = 39.7% vs. 33.7%. Average time with low blood glucose overnight from CGM in standard therapy vs. Omnipod 5 = 3.41% vs. 2.13%. Average time with low blood glucose during daytime from CGM in standard therapy vs. Omnipod 5 = 3.44% vs. 2.57%. Average A1c in standard therapy vs. Omnipod 5 = 7.4% vs. 6.9%. Sherr JL, et al. Diabetes Care (2022)."

These modules are not a replacement for medical advice or training. Please always speak to a qualified healthcare professional about your options.