Overcoming Challenges and Simplifying Diabetes Management with the Omnipod® 5 Automated Insulin Delivery System

The Omnipod 5 Automated Insulin Delivery (AID) System is a transformative step in diabetes care. The system merges the benefits and simplicity of a wearable, tubeless design with AID technology. This is a powerful option for the management of type 1 diabetes, especially for children and young adults. 

This article explores clinical guidelines as well as some educational strategies and real-world examples that demonstrate the impact that Omnipod 5 can have in diabetes management. 

This article draws from the webinar linked below, where healthcare experts discuss the topics in greater detail.

What is Omnipod 5?

The Omnipod 5 System stands out for its ability to simplify diabetes management through its innovative features. The system includes a wearable, tubeless insulin pump (Pod) that communicates directly with a compatible continuous glucose monitor (CGM)*. Its algorithm, built into the Pod, ensures automated insulin delivery, even when the Controller is out of range.

Pod and sensor with Bluetooth shown without necessary adhesive Pod and sensor with Bluetooth shown without necessary adhesive
Pod and sensor shown without necessary adhesive. Screen for illustrative purposes only.

The system’s customisable glucose targets allow for management tailored to the patient’s daily schedule. This adaptability reduces the burden on patients and caregivers, offering peace of mind and making day-to-day diabetes management more manageable.1,2

Additionally, Omnipod 5 simplifies data sharing and your ability to monitor patients’ progress through automatic and wireless uploads to the Glooko® platform. This feature enables healthcare teams to review patient data in real time, facilitating timely adjustments and more effective consultations. 

Clinical Guidelines and Equitable Access

Hybrid closed-loop systems like Omnipod 5 are now a recommended option for managing type 1 diabetes under the UK National Institute for Health and Care Excellence (NICE) guidelines.3 These systems are particularly advised for children, young people, and adults experiencing challenges such as suboptimal glycaemia or problematic hypoglycaemia.3 NICE estimates that over 150,000 individuals with type 1 diabetes in the UK will gain access to these systems within the next five years.4 

Equitable access is crucial. Research indicates that individuals from lower socioeconomic groups and ethnically diverse populations often face barriers to adopting advanced diabetes technologies.5 Keep this in mind in your practice to help address these disparities and ensure that all eligible patients can benefit from hybrid closed-loop systems like Omnipod 5.

Streamlined Education and Implementation

Transitioning to Omnipod 5 requires structured education to build confidence in patients and families.6 Tailored strategies, like pre-session workbooks and interactive training, prepare new users for the system, reducing in-clinic training time.7 Providing personalized support can address language barriers and other needs.7 Using standardized pump settings based on total daily insulin (TDI) can streamline the process, enabling a smoother transition to AID.6 

As a healthcare professional, you are essential to guiding patients through the initiation and optimisation of Omnipod 5. 

 

See How Omnipod 5 Transforms Diabetes Care in Real Life

 

Case 1: Early Adoption of Omnipod 5 Empowers a Family

An 8-year-old boy with type 1 diabetes started on Omnipod 5 shortly after his diagnosis. His initial HbA1c was alarmingly high at 108 mmol/mol (12%). 

Watch the webinar to learn how the system’s automation allowed the family to manage glucose levels with minimal manual intervention. The flexibility of customisable glucose targets and the Activity Feature proved invaluable, particularly during periods of high activity. This case highlights how early adoption of Omnipod 5 can empower families and improve clinical outcomes. 

Case 2: Omnipod 5 Helps a Patient Overcome Health Challenges

A 19-year-old male with a history of poorly managed diabetes and recurrent diabetic ketoacidosis presented a unique challenge. 

Watch the webinar to learn how simplified carbohydrate counting strategies were introduced to address difficulties with consistent meal bolusing. By leveraging Omnipod 5’s automation, the patient experienced improved glycemic outcomes and a renewed sense of control over his diabetes. 

Want to learn more? 

Access the full webinar recording and hear directly from leading diabetes experts like Dr. Ruben Willemsen and Francesca Annan from the United Kingdom.

* Sensor sold separately and requires a separate prescription.

It is recommended to keep the controller nearby to address important alerts/alarms.

Must be connected to Wi-Fi or cellular data, and Omnipod 5 users must have Wi-Fi or cellular data access to receive updates in Glooko.

References:

1.    Hood KK, et al. Diabetes Obes Metab. 2024;26(12):5569-5579. Single-arm, multicentre prospective study in 125 paediatric participants with T1D (83 children 6–11.9 yrs; 42 adolescents 12–17.9 yrs). All used Omnipod 5 for 3 months; validated age- and role-specific questionnaires (PAID, HCS, WHO-5, PSQI, IDSS, SUS) were completed by participants and caregivers at baseline and study end to evaluate psychosocial outcomes. Parents of children reported improved quality of life and mental well-being compared to prior therapy. Parents of children felt confident in staying safe from the risk of hypoglycemia compared to prior therapy—mean hypoglycemia confidence survey (HCS) score of 3.65 vs. 3.52.

2.    Polonsky WH, et al. Diabetes Research and Clinical Practice. 2022;190:109998. Single-arm, multicentre prospective study in 115 adults with T1D (18–70 yrs). All used Omnipod 5 for 3 months; psychosocial questionnaires (T1-DDS, HCS, WHO-5, PSQI, IDSS, DTSQ, SUS) were completed at baseline and study end. Adults reported reduced diabetes distress compared to prior therapy—mean diabetes distress scale (T1-DDS) score of 1.48 vs. 1.64. Adult users felt confident in staying safe from the risk of hypoglycemia compared to prior therapy—mean hypoglycemia confidence survey (HCS) score of 3.59 vs. 3.34.

3.    National Institute for Health and Care Excellence (NICE). Hybrid Closed Loop Systems for Managing Blood Glucose Levels in Type 1 Diabetes (Technology Appraisal TA943). December 19, 2023. Accessed June 4, 2025. https://www.nice.org.uk/guidance/ta943

4.    NICE approves hybrid closed loop for the majority of people living with type 1 diabetes in England and Wales. Breakthrough T1D UK. Published December 19, 2023. Accessed August 27, 2025. https://breakthrought1d.org.uk/news/nice-approves-hybrid-closed-loop-for-the-majority-of-people-living-with-type-1-diabetes-in-england-and-wales/

5.    Phillip M, et al. Consensus Recommendations for the Use of Automated Insulin Delivery Technologies in Clinical Practice. Endocr Rev. 2023;44(2):254-280.

6.    Berget C, et al. Clinical Implementation of the Omnipod 5 Automated Insulin Delivery System: Key Considerations for Training and Onboarding People With Diabetes. Clin Diabetes. 2022;40(2):168-184.

7.    Pemberton J, et al. Enhancing equity in access to automated insulin delivery systems in an ethnically and socioeconomically diverse group of children with type 1 diabetes. BMJ Open Diabetes Research & Care. 2024;12:e004045.

The Omnipod 5 Automated Insulin Delivery System is a single hormone insulin delivery system intended to deliver U-100 insulin subcutaneously for the management of type 1 diabetes in persons aged 2 and older requiring insulin. The Omnipod 5 System is intended for single patient use. The Omnipod 5 System is indicated for use with NovoLog®/NovoRapid®, Humalog®, Trurapi®/Truvelog®/Insulin aspart Sanofi®, Kirsty®, and Admelog/Insulin lispro Sanofi U-100 insulin. Refer to the Omnipod® 5 Automated Insulin Delivery System User Guide and www.omnipod.com/safety for complete safety information including indications,
contraindications, warnings, cautions, and instructions.